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TR inhibits BCR-ABL/STAT5 signaling pathway. (A) Western blot analysis of pY247AB, pY177AB, pY694STAT5, STAT5, pY207CRKL, pY308AKT, AKT, and pT180/Y182p38. K562 cells were treated with TR total extract for 24 and 48 h at 0.5 mg/mL; (B) Normalization of protein level expression using the ImageJ software. Values are mean ± SD of biological duplicates. **** p-value ≤ 0.0001, *** p-value ≤ 0.001, ** p-value ≤ 0.01, * p-value ≤ 0.05, ns p-value > 0.05 vs. control cells.
