Table 1.
Baseline characteristics of the study population. Characteristics of the study population are described using means ± s.d. (standard deviation) or median and range for continuous variables, number of cases with relative percentages reported in parentheses for categorical variables. Abbreviations: ΔT2T1 MRI index, volumetric difference between preoperative tumor volumes on T2 and T1 weighted MRI images; EOR, extent of surgical resection.
| Parameters | Value (N and %, Mean ± s.d. or Median and Range) |
|---|---|
| No. of patients | 155 |
| Sex | |
| Female | 59 (38.06%) |
| Male | 96 (61.94%) |
| Age (years) | 37 18-73) |
| Tumor side | |
| Left | 88 (56.77%) |
| Right | 67 (43.23%) |
| Tumor site | |
| Frontal | 50 (32.26%) |
| Parietal | 13 (8.39%) |
| Temporal | 24 (15.48%) |
| Insular | 65 (41.94%) |
| Occipital | 3 (1.93%) |
| Preoperative tumor volume computed on T2-weighted MRI images, cm3 | 48 (6–144) |
| Preoperative ΔT2T1 MRI index, cm3 | 12 (0-55) |
| Preoperative ΔVT2T1 MRI index | |
| <18 cm3 | 88 (56.67%) |
| ≥18 cm3 | 67 (43.23%) |
| EOR% | 88 (38–100) |
| EOR% | |
| 100 | 30 (19.36%) |
| 99–90 | 43 (27.74%) |
| 70–89 | 45 (29.03%) |
| ≤69 | 37 (23.87%) |
| Postoperative residual tumor volume computed on T2-weighted MRI images, cm3 | 10 (0–44) |
| Molecular class | |
| Oligodendroglioma IDH1/2 mutated 1p-19q codeleted | 44 (28.39%) |
| Astrocytoma IDH 1/2 mutated 1p-19q non codeleted | 93 (60.00%) |
| Astrocytoma IDH 1/2 wild type | 18 (11.61%) |
| MGMT Methylation status yes vs. no |
136 vs. 19 (87.74% vs. 12.26%) |
| Intraoperative protocol | |
| Awake surgery | 113 (72.90%) |
| General anesthesia | 42 (27.10%) |
| Time between seizure onset and surgery | 6 months (range 4–20 months) |