Table 1.

Potential clinical uses of galectins in the treatment of cancers and endometriosis.

Therapy Type	Examples	Targets	Effect
Galectin-1 inhibitors [44]	Thiodigalactoside Anginex OTX008 Davanat	Breast cancer Ovarian cancer Lung cancer Colon cancer Head and neck cancers Melanoma Endometriosis	Induce apoptosis, reduce angiogenesis, restore T cell surveillance, reduce lung metastasis
Galectin-3 inhibitors [44]	G3-C12 Modified Citrus Pectin (MCP), GCS-100	Leukemia Ovarian cancer Prostate cancer Colon cancer Endometriosis	Induce apoptosis, inhibit tumor growth/cell cycle inhibition, increase responsiveness to chemotherapy, increase T cell activity
Recombinant Galectin-9 [46]	hG9NC	Hematological cancer Dermatological cancers Gastrointestinal cancers	Prevent T cell apoptosis Induce apoptosis of malignant cells