Figure 1.

Schematic representations of the Leukocyte Receptor Complex (LRC) region and typical KIR A and B genotypes. Map of the Leukocyte Receptor Complex. The Leukocyte Receptor Complex (LRC) is formed by a cluster of genes that encode a family of proteins that contain immunoglobulin-like domains. These include the families “killer immunoglobulin-like receptors (KIR), “leukocyte immunoglobulin-like receptor” (LILR), and “leukocyte-associated immunoglobulin-like receptor” (LAIR). The “signaling lectins” (SIGLECs) and members of the family CD66 are found close to LCR.