Table 3.
Frequency distribution of HLA alleles between CRC cases and controls.
| HLA Allele | AF CRC Cases | AF Healthy Controls | P value | OR | 95% CI | Padj |
|---|---|---|---|---|---|---|
| DRB1*11:01 | 0.1002 | 0.0785 | 0.0137 | 1.32 | 1.06–1.65 | 0.0961 |
| C*07:01 | 0.1304 | 0.1543 | 0.0321 | 0.82 | 0.69–0.98 | 0.1774 |
| C*12:03 | 0.0689 | 0.0534 | 0.0443 | 1.30 | 1.01–1.67 | 0.1774 |
| A*02:01 | 0.2264 | 0.2519 | 0.0576 | 0.87 | 0.75–1.00 | 0.3453 |
| A*29:02 | 0.0848 | 0.0730 | 0.1554 | 1.18 | 0.94–1.50 | 0.4662 |
| DRB1*04:01 | 0.0467 | 0.0562 | 0.1751 | 0.82 | 0.62–1.09 | 0.6128 |
| B*35:01 | 0.0583 | 0.0511 | 0.3096 | 1.15 | 0.88–1.52 | 0.8689 |
| C*16:01 | 0.0843 | 0.0757 | 0.3136 | 1.13 | 0.89–1.42 | 0.6060 |
| B*44:03 | 0.1071 | 0.0976 | 0.3240 | 1.11 | 0.90–1.35 | 0.8689 |
| C*07:02 | 0.0817 | 0.0897 | 0.3641 | 0.90 | 0.72–1.13 | 0.6060 |
AF: allele frequency; OR: odds ratio; CI: confidence interval; Padj: p-values adjusted and corrected for FDR using the Benjamini-Hochberg test.