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. 2020 Feb 11;21(4):1210. doi: 10.3390/ijms21041210

Table 3.

Calcium-independent IQ, IQ-like, and non-IQ.

Calmodulin-Binding Motifs in Dictyostelium
Full IQ motifs ((F/I/L/V)Qxxx(R/K)Gxxx(R/K)xx(F/I/L/V/W/Y))
CaMBP (gene) Dictybase IQ Binding Sequence
MhcA (mhcA) DDB0191444 IQ1 IQAA TRGWIARKVYK
Myo1E(myoE) DDB0216200 IQ1 IQKTWRGYRARSKWN
Myo1F(myoF) DDB0220021 IQ1 IQRVWRGYKVRKWYD
Myo5A(myoH) DDB0233685 IQ1 IQKIWRGYTDRKAYI
Myo5B(myoJ) DDB0185050 IQ1 IQKRWKGYLYRKRYK
IQ-like motifs ((F/I/L/V)Qxxx(R/K)xxxxxxxx)
DwwA (dwwA) DDB0216188 IQ1 IQRT FRNHKKQSY
MhcA (mhcA) DDB0191444 IQ2 IQQNLRAYIDFKSW
Myo1A(myoA) DDB0215392 IQ2 IQRT YRGWLLVRECV
Myo1B(myoB) DDB0191351 IQ1 IQKAFRNWKAKKHSL
Myo1C(myoC) DDB0215355 IQ3 IQGYFRAWKQASPFF
Myo1E(myoE) DDB0216200 IQ2 IQLF YRSYRYKKWFR
Myo5A(myoH) DDB0233685 IQ2 FQSL IRSYLQQLEYN
Myo5A(myoH) DDB0233685 IQ3 LQSL IRTNELEKQFN
Myo5A(myoH) DDB0233685 IQ4 FQSL LRRLEDSKEFN
Myo5A(myoH) DDB0233685 IQ5 IQSLWRSNLAKKQLK
Myo5B(myoJ) DDB0185050 IQ2 IQTK LRSVHAKQQLS
Myo5B(myoJ) DDB0185050 IQ3 IQKVWRAHRDRVQYQ
Myo5B(myoJ) DDB0185050 IQ4 IQTVMRRHLFSEQVH
Myo5B(myoJ) DDB0185050 IQ5 LQTK IRQILSKREVD
Myo5B(myoJ) DDB0185050 IQ6 IQARWRMKLAKRVYI
MyoG (myoG) DDB0232322 IQ1 IQSTWRMYLIRKRFI
MyoG (myoG) DDB0232322 IQ2 IQKNTRRWLVQKRYQ
MyoG (myoG) DDB0232322 IQ4 IQTHLRSLLSKDYSY
MyoI (myoI) DDB0185049 IQ1 IQSVWRMYRCKKRYQ
MyoI (myoI) DDB0185049 IQ4 VQNNIRSFIARRHSR
MyoM (myoM) DDB0191100 IQ1 IQAF FKMIKIRNQYK
MyoM (myoM) DDB0191100 IQ2 LQTL IRAQRAKKDFE
NumA (numA) DDB0231257 IQ1 LQKQQKIYKDLERF
RgaA (rgaA) DDB0191437 IQ1 IQEL KRNLVSEVRR
RgaA (rgaA) DDB0191437 IQ2 LQTE PKYLAGLVYL
VatM IQLA LRTATTRSGA
Non-IQ motifs
Myo1A(myoA) DDB0215392 IQ1 IGSVWKMYKQRIKWYL
Myo1C(myoC) DDB0215355 IQ1 IKNAYRNYKAFQFEC
Myo1C(myoC) DDB0215355 IQ2 IKNAFRNYKLYRQRC
Myo1D(myoD) DDB0191347 IQ1 LQRFFLRFTLMSYYY
Myo1F(myoF) DDB0220021 IQ2 IQTYYLRYKVLTYIK
MyoG (myoG) DDB0232322 IQ3 LESFSRMVIFRAPYL
MyoI (myoI) DDB0185049 IQ2 LGAAMLSHSSRRDFQ
MyoI (myoI) DDB0185049 IQ3 IKGFFKMLTYQKQFK

The critical amino acids in the motifs are highlighted in green. Revised and updated from [13,14].