Figure 2.

(a) Monomeric Aβ42, Aβ40, and their ratio (Aβ42/Aβ40) in the conditioned medium of rat primary cerebral cortex cells treated with 1 at the indicated concentrations for 24 h. (b) Toxic Aβ oligomers, monomeric Aβ42, and their ratio (toxic oligomers/Aβ42) in the conditioned medium of rat primary cerebral cortex cells treated with 1 at the indicated concentrations for 6 h. The data are presented as mean ± SD (n = 3). ^**p < 0.01 versus Veh (vehicle). n.s.: not significant. Red or black dots represent each value.