Figure 1.

Expression of α2 adrenergic receptor (α2-AR) subtypes in carbon tetrachloride (CCl₄)-treated and bile duct-ligated (BDL) mouse models of liver fibrosis/cirrhosis. (A–C) Expression of α2a-AR, α2b-AR, and α2c-AR mRNA in liver tissues from mice treated with CCl₄ and controls, measured after 4 weeks using RT-qPCR. (D–F) Hepatic expression of α2a-AR, α2b-AR, and α2c-AR in mice after 4 weeks of BDL vs a sham operation (SO), measured using RT-qPCR. mRNA levels are shown as the mean ± standard error of the mean (SEM) (n = 4). Differences between both groups were analyzed using Student’s t-test. Statistical significance is indicated as follows: p < 0.05 (*); p < 0.01 (**); p < 0.001 (***).