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(a) Cluster of Cassiae semen ligands binding to structure S1 (5-HT2C in an agonist-bound active conformation; chain A of PDBID: 6BQG). (b) Cluster of Cassiae semen ligands binding to structure S2 (5-HT2C in an antagonist-bound inactive conformation; chain A of PDBID: 6BQH).
