Table 3.
Common ligand-binding residues of selected ligands. 1: the existence of a contact between the residue (rows) and the ligand (columns) if any atom of the residue and ligand lies within 4 Angstroms of each other. Green-colored rows indicate residues of especial interest, discussed in text.
| Residue | S1-LOC | S1-c03 | S1-c09 | S1-c22 | S1-c34 | S1-c49 | S2-BEN | S2-c06 | S2-c29 | S2-c47 | Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Ser110 | 1 | 1 | 2 | ||||||||
| Ser118 | 1 | 1 | 1 | 1 | 4 | ||||||
| Trp130 | 1 | 1 | 2 | ||||||||
| Ile131 | 1 | 1 | 2 | ||||||||
| Asp134 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 9 | |
| Val135 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 9 | |
| Ser138 | 1 | 1 | 1 | 1 | 1 | 5 | |||||
| Thr139 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 7 | |||
| ILE142 | 1 | 1 | 1 | 3 | |||||||
| Val185 | 1 | 1 | 2 | ||||||||
| Val208 | 1 | 1 | 1 | 1 | 4 | ||||||
| Leu209 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 9 | |
| Phe214 | 1 | 1 | 1 | 1 | 4 | ||||||
| Val215 | 1 | 1 | 1 | 1 | 1 | 5 | |||||
| Gly218 | 1 | 1 | 1 | 1 | 1 | 5 | |||||
| Ser219 | 1 | 1 | 1 | 3 | |||||||
| Ala222 | 1 | 1 | 1 | 1 | 1 | 5 | |||||
| Phe223 | 1 | 1 | 2 | ||||||||
| Trp324 | 1 | 1 | 1 | 1 | 4 | ||||||
| Phe327 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 10 |
| Phe328 | 1 | 1 | 1 | 1 | 1 | 1 | 6 | ||||
| Asn331 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 8 | ||
| Ser334 | 1 | 1 | 1 | 3 | |||||||
| Glu343 | 1 | 1 | 2 | ||||||||
| Glu347 | 1 | 1 | 1 | 1 | 4 | ||||||
| Leu350 | 1 | 1 | 1 | 1 | 4 | ||||||
| Asn351 | 1 | 1 | 1 | 1 | 4 | ||||||
| Val354 | 1 | 1 | 1 | 1 | 1 | 5 | |||||
| Tyr358 | 1 | 1 | 1 | 1 | 4 |