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Schematic illustration of the concept of the Na/K-ATPase signaling-mediated oxidant-amplification loop. +, stimulating effect; - attenuating effect; CTS, cardiotonic steroids; ROS, reactive oxygen species; α1, Na/K-ATPase α1 subunit; mTOR, the mammalian target of rapamycin; miR-29b-3p, microRNA-29b-3p.
