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. 2020 Feb 15;21(4):1312. doi: 10.3390/ijms21041312

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Specificity of [¹²⁵I]I-PIB-(HE)₃-Z_HER3:08698-DOTAGA and [¹¹¹In]In-(HE)₃-Z_HER3:08698-DOTAGA tumor targeting in Balb/c nu/nu mice bearing BxPC-3 xenografts. The uptake of both imaging probes in tumors was significantly (* p < 0.0001) decreased when a large excess of non-labeled HER3 affibody molecule was administered. Data are presented as average ± SD for four mice.