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. 2020 Feb 15;21(4):1307. doi: 10.3390/ijms21041307

Figure 3.

Figure 3

(A) Human oral mucosal stem cells (HOMSCs) were treated from 0 up to 96 h with several CEMP1-p4 concentrations where 4 µg/mL was shown to be optimal for cell proliferation. (B) CEMP1-p4 at 4 mg/mL increases alkaline phosphatase (ALP)-specific activity on HOMSCs at 7 and 14 days. (C) Representative images showing ARS after osteogenic induction on HOMSCs by CEMP1-p4 at 4 mg/mL during 3, 7, and 14 d of culture. (D) Mineral formation was quantified by cetylpyridinium chloride (CPC), showing that CEMP1-p4 is a potent inductor of calcium salts. *p < 0.05.