Table 3.

Summary of zinc finger proteins described in the literature and discussed in this review.

Name	Gene ID	Zinc Finger Type	Description and Function	References
Bwc2	CNE01220	ZnF_C4	Sexual filamentation and fungal virulence	[70,71]
Cir1	CNAG_04864CNJ02920	ZnF_C4	Iron uptake, iron homeostasis, and virulence	[89,93]
Cqs2	CNF00370	Znf_C2H2	Important component of the Qsp1-signaling cascade required for sexual reproduction	[82]
Crz1	CNA01450	Znf_C2H2	Regulates the sporulation process	[68]
Crz1	CNAG_00156	Znf_C2H2	Cell integrity; Proliferation and survival under reduced aeration; Biofilm formation and susceptibility to fluconazole.	[99]
Gat1	CNAG_00193	ZnF_C4	Nitrogen uptake and metabolism	[104]
Gis1	CNAG_02338	Znf-C2HC	Sterol biosynthesis and fluconazole and oxidative stress sensitivity	[103]
Mig1	CNAG_06327	Znf_C2H2	Mitochondrial function and azole drug susceptibility	[102]
sp1	CNAG_00156	Znf_C2H2	Cell wall stability, nitrosative stress, extracellular capsule production, and fungal virulence	[87]
STE12αp	CND05810	Znf_C2H2	Haploid filamentation and fungal virulence	[74,75,77]
STE12ap		Znf_C2H2	Capsule formation and fungal virulence; Capsule-associated genes expression;	[76,86]
Zap1	CNBG_4460	Znf_C2H2	Growth in zinc-limiting conditions Expression of ZRT, IRT-like protein (ZIP) zinc transporters and distinct zinc-binding proteins; Fungal virulence	[96]
Zfp1	CNAG_07329	Znf_C2H2	Sexual reproduction and fungal virulence	[79]
Znf1	CND05720	Znf_C4HC3	Not essential for Cryptococcus dimorphic hyphal growth	[58]
Znf2	CNG02160	Znf_C2H2	Master activator of the yeast to hyphal transition; Key regulator for hyphal growth	[58,61,62,63]
Znf3	CNK01880	Znf_C2H2	Hyphal development during unisexual and bisexual reproduction	[59]
Znf3	CNAG_02700	Znf_C2H2	Link between RNAi silencing and sexual development	[65]
Znf9	CNAG_01273	Znf_C2HC	Sterol biosynthesis; Fluconazole and oxidative stress sensitivity	[103]