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. 2020 Feb 15;21(4):1316. doi: 10.3390/ijms21041316

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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SAA induced increase in urinary protein in SAA treated mice. Male ApoE⁻/⁻ mice were allocated into 4 treatment arms and administered with vehicle (control), LPS, SAA alone, or SAA in combination with HDL. Urine was collected 4 weeks (left panel A) or 18 weeks (right panel B) after commencement of treatment and analyzed for total protein as described in methods. Data shows mean ± SD for young cohort, with mice numbers control (n = 7), LPS (n = 8), SAA (n = 6), and HDL/SAA (n = 6); and old cohort, control (n = 8), LPS (n = 8), SAA (n = 6), and HDL/SAA (n = 6). * Different to the corresponding control and LPS group, p < 0.05. ^# Different to the corresponding HDL/SAA group, p < 0.05.