Table 4.
Summary of findings from the meta-analysis published by Hu et al. [81] in 2019.
| Outcome | Number of Studies | Finding for Marine n-3 Fatty Acids Versus Placebo | Finding if Data from REDUCE-IT Removed |
|---|---|---|---|
| Rate Ratio [95% Confidence Interval] (p) | Rate Ratio [95% Confidence Interval] (p) | ||
| Myocardial infarction | 13 | 0.88 [0.83, 0.94] (<0.001) | 0.92 [0.86, 0.99] (0.020) |
| CHD death | 12 | 0.92 [0.86, 0.98] (0.014) | Outcome not reported in REDUCE-IT |
| Total CHD | 13 | 0.93 [0.89, 0.96] (<0.001) | 0.95 [0.91, 0.99] (0.008) |
| Total stroke | 13 | 1.02 [0.95, 1.10] (0.569) | 1.05 [0.98, 1.14] (0.183) |
| CVD Death | 12 | 0.92 [0.88, 0.97] (0.003) | 0.93 [0.88, 0.99] (0.013) |
| Total CVD | 13 | 0.95 [0.82, 0.98] (<0.001) | 0.97 [0.94, 0.99] (0.015) |
| Major vascular events | 13 | 0.95 [0.93, 0.98] (<0.001) | 0.97 [0.94, 1.00] 90.058) |
Abbreviations: CHD, coronary heart disease; CVD, cardiovascular disease.