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Verapamil sensitized ABCB1-overexpressing cells to WYE-354. WYE-354 co-treated with verapamil (5 μM) decreased the survival rate of WYE-354 in (A) KB-C2 cells and (B) HEK293/ABCB1 cells. All of the experiments were performed at least three times independently. Data are shown as mean ± standard deviation (SD). * represents p < 0.05, compared with the control group.
