Table 2.
Summary of exosomal lncRNA studies in CRC patients.
| lncRNA | Number of CRC Patients * |
Sample Type | Exosome Isolation Method | Expression | Type of Biomarker | Refs |
|---|---|---|---|---|---|---|
| UCA1 | 20 | serum | Ultracentrifugation, ExoQuick |
Downregulated | Diagnostic | [115] |
| CCAT2 | 100 | serum | ExoQuick |
upregulated | Diagnostic | [116] |
| LNCV6_116109, LNCV6_98390, LNCV6_38772, LNCV_108266, LNCV6_84003, LNCV6_98602 | 50 | plasma | Ultracentrifugation | upregulated | Diagnostic | [117] |
| RPPH1 | 52 | plasma | Ultracentrifugation, SBI |
upregulated | Diagnostic And prognostic |
[118] |
| CRNDE-h | 148 | serum | ExoQuick | Upregulated | Diagnostic and prognostic | [113] |
| GAS5 | 158 | Serum | Ultracentrifugation | Downregulated | Diagnostic and Prognostic | [109] |
| HOTTIP | 100 | serum | Exosome isolation kit (ThermoFisher Scientific®, Cat-Nr.: 4478360) | Downregulated | Diagnostic and Prognostic |
[119] |
* number of CRC patients who had blood samples drawn which were utilized for exosomal analysis.