Table 3.
Summary of exosomal circRNA studies in CRC patients.
| circRNA | Number of CRC Patients * |
Sample Type | Exosome Isolation Method | Expression | Type of Biomarker | Refs |
|---|---|---|---|---|---|---|
| hsa-circ-0005100 (circFMN2) | 35 | serum | ultracentrifugation | Upregulated | Prognostic | [131] |
| hsa-circ-0067835 (circIFT80) | 58 | plasma | ultracentrifugation | Upregulated | Prognostic | [132] |
| hsa-circ-0000338 | 17 | serum | QIAGEN exoRNeasy Midi Kit, ultracentrifugation | Upregulated | Predictive | [133] |
| hsa-circ-0004771 | 135 | serum | Invitrogen™ Total Exosome Isolation Kits | Upregulated | Diagnostic And Prognostic |
[134] |
* number of CRC patients who had blood samples drawn which were utilized for exosomal analysis.