Figure 2.

Trend of mean log₂RQ and distribution of the difference between week 2 and baseline according to pCR for ct-miR-148a-3p and ct-miR-374a-5p. Panel (A) and (C) report the trend of mean log₂RQ for ct-mR-148a-3p and ct-miR-374a-5p according to pathological complete response (pCR), respectively. Panel (B) and (D) report the distribution of the difference between log2RQ of each ct-miRNA at T1 and T0 according to pCR. Red line indicates patients with pCR and blue line indicates patients without pCR. Panels (B) and (D) report the distribution of log2RQ difference between week 2 and baseline for ct-mR-148a-3p and ct-miR-374a-5p according to pCR, respectively. p-Value of the Kruskal-Wallis test for the comparisons of log2RQ difference between patients with and without pCR is reported.