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GAL3 deletion induces chondrocyte catabolism. qRT-PCR analysis of Adamts-5 (A), Mmp3 (B), Mmp13 and type X collagen (C) mRNA expression in cultured chondrocytes from articular cartilage of Gal3−/− and WT newborn mice with and without IL-1β stimulation (10 ng/mL) (201-LB/CF, R&D Systems, Lille, France) (n = 5 independent experiments). Horizontal bars were medians, box edges are Q1–Q3 and whiskers are range. Two-tailed Mann–Whitney U test between WT and Gal3−/−.
