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Percentage of elevation of IgG, IgM, and IgA antibodies against zonulin+occludin in 94 patients positive for ASCA and in 94 healthy controls. Dotted lines indicate the cutoff for positivity used in each assay, as calculated by ROC analysis. The percentage of elevation is indicated on top of each distribution, while bars indicate the corresponding median. The AUC for zonulin+occludin IgG was 0.73, 0.70 for zonulin+occludin IgM, and 0.74 for zonulin+occludin IgA.
