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. 2020 Feb 22;21(4):1495. doi: 10.3390/ijms21041495

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of PAD2, PAD3 and PAD4 isozyme-specific inhibitor treatment on EV modal size in GBM cells, following 1 h treatment. (A) Modal size of EVs released from LN18 cells and LN229 cells, respectively, following 1 h PAD2 and PAD4 inhibitor treatment. (B) Modal size of EVs released from LN18 cells and LN229 cells, respectively, following 1 h PAD3 inhibitor treatment. Exact p-values are indicated, error bars show SD (* indicates significant differences with p < 0.05; ns = non-significant change; n = 3 biological replicates for all).