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. 2020 Jan 22;12(2):274. doi: 10.3390/cancers12020274

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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DCLK1 mRNA expression in tumor tissues is significantly correlated with immune infiltration. Estimated fraction of immune cells in tumor tissues of COAD (A) and STAD (B) was visualized by QuanTIseq analysis. Among all the immune cell types, macrophages (M1 + M2) represented the major population in COAD and STAD. Correlation analysis shows that DCLK1 expression is significantly correlated with CD8+ T cell (C), M2 macrophage (D), and Treg (E) in COAD. DCLK1 expression is also significantly correlated with M2 macrophage (G) and Treg (H) and shows a weak correlation with CD8+ T cells (F) in STAD.