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. 2020 Jan 22;12(2):274. doi: 10.3390/cancers12020274

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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DCLK1/CD8 status predicts DSS of colon and stomach cancer patients. Kaplan–Meier analysis of composite DCLK1 and CD8 status based on mRNA expression in COAD (A) and STAD (B). DCLK1Lo/CD8Lo (green line) patients presented with better survival times than DCLK1Hi/ CD8Hi (red line) for COAD and STAD. DSS times of COAD and STAD patients with lower DCLK and higher CD8 (yellow line) were better than higher DCLK1 and higher CD8 (red line). Cox regression analysis of patients in COAD (C) and STAD (D) indicated that combined high DCLK1 and high CD8 mRNA expression is an independent indicator of prognosis. DCLK1 Lo/CD8Lo was used as the control group for all statistical comparisons.