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. 2020 Feb 4;12(2):353. doi: 10.3390/cancers12020353

Figure 3.

Figure 3

POU6F2-AS2 and AC022126.1 cfRNA transcripts are highly expressed in lung cancer. (A) Plasma expression of POU6F2-AS2 as profiled by total cfRNA sequencing in healthy donors (n = 4) and NSCLC (n = 11). Plasma expression of POU6F2-AS2 as profiled by real-time digital droplet PCR (RT-ddPCR) (B). in healthy donors (n = 37) and NSCLC (n = 84) patients (C). in healthy donors (n = 37) and early stage NSCLC (n = 39) patients (D). in healthy donors (n = 37) and late stage NSCLC (n = 45) patients. Plasma expression of AC022126.1 as profiled by (E). total cfRNA sequencing (n = 4 heathy donors; n = 11 NSCLC patients) and (F). by ddPCR (n = 28 heathy donors; n = 84 NSCLC patients). In (A–F) scatter dot-plots, the line indicates the mean; Student’s t-test p values are indicated.