Table 3.

The best five compounds of ADMET properties are calculated by Osiris molecular property explorer.

Properties	CID6917760	CID9820229	CID5221957	CID389556	CID10900930	AG1
Mutagenic	No	No	No	Partial	No	No
Tumorigenic	No	No	No	Partial	No	No
Irritant	No	No	No	No	No	No
Reproductive effect	No	No	No	No	No	No
cLogP	4.77	4.76	4.63	3.55	3.61	4.22
Solubility	ne–3.99	ne–4.41	ne–3.84	ne–4.38	ne–4.40	ne–5.18
MW	330	359	400	246	246	438
TPSA	19.03 Å2	22.27 Å2	38.06 Å2	31.58 Å2	31.58 Å2	106.2 Å2
Drug likeness	2.81	7.9	7.97	0.11	2.77	1.76
Drug score	0.62	0.59	0.62	0.36	0.70	0.48