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. 2020 Feb 23;21(4):1517. doi: 10.3390/ijms21041517

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Distribution of nanostructured lipid carriers containing GALNS in mouse tissues. Images different tissues in wild type mouse, (1a) confocal microscopy brain tissue, (1b) electronic microscopy nanoparticles inside of neuron cell, (2a) confocal microscopy lung tissue, (2b) electronic microscopy nanoparticles inside of pneumocyte cell, (3a) confocal microscopy liver tissue, (3b) electronic microscopy nanoparticles inside of hepatocyte cells, (4a) confocal microscopy spleen tissue, (4b) electronic microscopy nanoparticles inside of macrophages cells, (5a) confocal microscopy kidney tissue, (5b) confocal microscopy renal tubule cells, (6a) confocal microscopy muscle tissue, (6b) confocal microscopy fibroblast cell, (7) images of mouse cartilage of mice at different zoom, showing that the cell inside of the cartilage contains nanoparticles (pink color) (7a) picture of cartilage ×20 zoom, (7b) picture of cartilage ×40 zoom, (7c) picture of cartilage ×63 zoom, (7d) picture of cartilage ×100 zoom.