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. 2020 Feb 22;21(4):1515. doi: 10.3390/ijms21041515

Figure 5.

Figure 5

Compound E4 reduces α-syn levels and protects against MPP+ toxicity in vitro. (A) N2a cells were transfected with A53T α-syn plasmid and then treated with E4 at indicated concentration. Data are presented as the mean ± SEM from 3 independent experiments. (B) Bright field of PC12 cells after incubation with E4 (1 μM) present or absence of CQ (20 μM) in MPP+ (1 mM) treated cells. Scale bar: 50 μm. (C) Cell viability of E4 present or absence of CQ against MPP+ induced cell injury. Data are presented as the mean ± SEM from three independent experiments. * p < 0.05, ** p < 0.01, # p < 0.05, n.s. not significant.