Figure 2.

The knockout of TSG101 causes a dissociation of a subset of early endosomes from recycling endosomes Confocal microscopic images of TSG101 conditional knockout fibroblasts 48 h after infection with a pBabe-Cre virus (Tsg101^-/-) and their isogenic control cells expressing endogenous TSG101 (Tsg101^fl/fl), which were infected with the pBabe control vector. Cells were stained with antibodies against Rab11 (green) and Rabaptin-5 (red); bar represents 10 µm. Arrows indicate examples for a colocalization of both markers (yellow) in wildtype controls.