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. 2018 Nov 20;2018(11):MR000005. doi: 10.1002/14651858.MR000005.pub4

Glick 2006.

Methods Identification of subsequent full‐length publications
  • Searched electronic database

    • Embase, MEDLINE, and PubMed to November 2004

    • Person completing the search not reported

    • Searched by first, second, and last author and keywords

    • Matched abstract to full‐length publication by

      • Objectives

      • Methodology

      • Results

Data
  • Included 1147 abstracts presented at the 2000 American Transplant Congress

  • Included all abstracts except those withdrawn and those published prior to the meeting

Comparisons
  • Proportion of abstracts published

  • Mean/median time to publication

  • Cumulative proportion of abstracts published

  • 'Positive' versus not 'positive'

  • Oral versus poster presentation

  • Clinical research versus basic science research

  • RCT design versus observational versus case series versus other study design

  • Multi‐centered versus single center

  • US versus non‐US origin versus origin not specified

  • Industry sponsorship versus none

Outcomes
  • 607 of 1147 abstracts published

  • Proportion of abstracts published by time

    • Mean time to publication = 15.8 months (SD =10.6)

    • Median time to publication = 12 months

    • Cumulative proportion of abstracts published at 54 months showed proportion published = 53.0% (608/1147 abstracts)

  • Factors related to proportion of abstracts published included

    • 208/397 'positive' (defined as significant results) versus 95/234 not 'positive' abstract results published

    • 308/547 abstracts presented orally versus 299/600 abstracts presented as posters published

    • 306/653 abstracts describing clinical research versus 301/494 abstracts describing basic science research published

    • 39/64 abstracts with RCT design versus 333/647 abstracts with observational design versus 140/284 abstracts with case series design versus 95/152 abstracts with other study design published

    • 220/371 abstracts with multiple centers versus 387/776 abstracts with a single center published

    • 398/804 abstracts originating in the US versus 197/314 abstracts not originating in the US versus 12/29 abstracts with origin not specified published

    • Adjusted multivariate analysis showed the following variables associated with publication:

      • Industry sponsorship versus none (OR = 1.78; 95% CI = 1.04 to 3.06)

      • Basic science versus clinical (OR = 1.68; 95% CI = 1.32 to 2.14)

      • 'Non‐American center' versus 'American center' (OR = 1.67; 95% CI = 1.28 to 2.20)

      • Oral versus poster presentation (OR = 1.36; 95% CI = 1.07 to 1.73)

Notes
  • Surgery ‐ organ transplantation

  • Funding by the Alberta Heritage Foundation for Medical Research

Risk of bias
Item Authors' judgement Description
Sampling method? Yes Included all abstracts with reasonable exceptions.
Search for publications? Yes Searched 2 databases.
Follow‐up time? Yes The meeting had 48 months follow‐up.
Matching? Yes Matched by 3 different criteria.
Adjustment for confounding? Yes Examined association of positive results, type of presentation, type science, study design, multi‐center status, US origin, organ type, and industry sponsorship with publication using multivariable logistic regression analysis.