Methods |
Identification of subsequent full‐length publications
|
Data |
Included 186 abstracts presented at the 1999 to 2002 American College of Cardiology scientific meetings
Included 86 abstracts of late breaking RCTs reporting clinical outcomes, and 100 other randomly chosen RCTs; RCTs with non‐human participants were excluded
|
Comparisons |
Proportion of abstracts published, overall and by meeting
Median time to publication by whether 'late‐breaking' or not
Survival analysis of publication rate
'Positive' versus not 'positive'
Multi‐centered versus single center
'Late‐breaking' versus not 'late‐breaking'
|
Outcomes |
148 of 186 abstracts published
34/43 abstracts presented at the 1999 meeting, 36/48 at the 2000 meeting, 41/49 at the 2001 meeting, and 38/46 at the 2002 meeting published
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Proportion of abstracts published by time
Median time to publication = 11.5 months for 'late‐breaking' abstracts
Median time to publication = 22 months for abstracts that were not 'late‐breaking'
Survival analysis of proportion published at 60 months = 83.3%
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Factors related to proportion of abstracts published included
70/84 'positive' (defined as significant results) versus 78/102 not 'positive' abstract results published
74/93 'positive' (defined as experimental better than control) versus 74/93 not 'positive' abstract results published
55/63 abstracts with multiple centers versus 93/123 abstracts with a single center published
79/86 'late‐breaking' abstracts versus 69/100 abstracts that were not 'late‐breaking' published
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Notes |
|
Risk of bias |
Item |
Authors' judgement |
Description |
Sampling method? |
Yes |
Included a random selection of abstracts describing RCTs and al late breaking abstracts describing RCTs. |
Search for publications? |
Yes |
Searched 7 databases. |
Follow‐up time? |
Yes |
All meetings before 2002 had at least 48 months follow‐up. The meeting in 2002 only had 36 months follow‐up. |
Matching? |
Yes |
Matched by 3 different criteria. |
Adjustment for confounding? |
Yes |
Examined association of positive results, multi‐center status, and 'late‐breaking' status with publication using Chi2 or tests and time to publication using a multivariable proportional hazards analysis. |