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. Author manuscript; available in PMC: 2020 Sep 15.
Published in final edited form as: Cancer Res. 2020 Feb 11;80(6):1234–1245. doi: 10.1158/0008-5472.CAN-19-1382

Figure 3. ETV4 is necessary for estrogen regulated gene expression.

Figure 3.

A) The top estrogen-induced genes in wildtype Ishikawa cells (blue) have significantly reduced (**p-value > 0.01; *p-value < 0.05) estrogen induction in ETV4 KO clones as tested by RNA-seq. B) Comparison of fold changes in estrogen induced expression of all genes shows reduced estrogen response globally in knockout (y-axis) compared to wildtype (x-axis). C) Comparison of both knockout clones shows they share similar estrogen response patterns.