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. Author manuscript; available in PMC: 2020 Sep 15.
Published in final edited form as: Cancer Res. 2019 Nov 25;80(6):1258–1267. doi: 10.1158/0008-5472.CAN-19-0638

Fig. 1.

Fig. 1

MALDI MSI analysis of intracranial GBM12 PDX model: a) H&E stained serial tissue section demonstrating highly cellular tumor region, b) segmentation map of MALDI MSI data produced via bisecting k-means clustering (k = 8), whereby different clusters are labelled with different colors, and two separate clusters are indicated within the tumor region indicating spectral differences between these regions, c-e) MALDI MSI ion images of three different long chain acylcarnitines: c) myristoylcarnitine: m/z 410.2666, detected as [M+K]+ , d) palmitoylcarnitine: m/z 400.3422, detected as [M+H]+ , and e) stearoylcarnitine: m/z 428.3734, detected as [M+H]+ .