TABLE 2.
Subgroup analysis on the effects of whole-grain consumption on BMI
| Effect sizes, n | Mean (95% CI) | P: within1 | I 2,2 % | P: between | |
|---|---|---|---|---|---|
| Overall | 10 | 0.61 (0.54, 0.95) | <0.001 | 90.0 | |
| Sex | <0.001 | ||||
| Both | 8 | −0.11 (−0.34 to 0.13) | 0.38 | 0 | |
| Females | 2 | 1.63 (1.35–1.92) | <0.001 | 61.4 | |
| Baseline mean of BMI | 0.002 | ||||
| Nonobese (<30 kg/m2) | 2 | 0.01 (−0.42 to 0.43) | 0.98 | 0 | |
| Obese (≥30 kg/m2) | 8 | 0.74 (0.54–0.95) | <0.001 | 91.3 | |
| Health condition | <0.001 | ||||
| Healthy | 1 | −0.20 (−0.96 to 0.56) | 0.60 | 0 | |
| Unhealthy | 9 | 0.66 (0.47–0.85) | <0.001 | 90.6 | |
| Duration of intervention | 0.002 | ||||
| <8 wk | 3 | −0.00 (−0.43 to 0.42) | 0.98 | 0 | |
| ≥8 wk | 7 | 0.75 (0.55–0.95) | <0.001 | 92.4 | |
| Study design | <0.001 | ||||
| Parallel | 6 | 1.10 (0.86–1.35) | <0.001 | 90.6 | |
| Crossover | 4 | −0.02 (−0.30 to 0.25) | 0.87 | 0 | |
| Calorie restriction | 0.02 | ||||
| Hypocaloric diet | 2 | −0.55 (−1.55 to 0.46) | 0.28 | 0 | |
| Isocaloric diet | 8 | 0.65 (0.46–0.84) | <0.001 | 91.7 | |
| Intervention type | <0.001 | ||||
| Whole-grain diet | 4 | −0.11 (−0.43 to 0.20) | 0.47 | 0 | |
| Whole-grain products | 6 | 0.98 (0.76–1.21) | <0.001 | 91.3 | |
| Anthropometric measures as: | <0.001 | ||||
| Primary outcome variables | 5 | 1.00 (0.77–1.23) | <0.001 | 92.9 | |
| Secondary outcome variables | 5 | −0.10 (−0.40 to 0.21) | 0.53 | 0 |
Refers to the mean (95% CI).
Inconsistency, percentage of variation across studies due to heterogeneity.