Table 3. Overall comparison of changes from baseline within and between oxaloacetate/vitamin C and placebo for parts A and B participants.

Characteristics	Oxaloacetate			Placebo			P-valueb)
	Mean improvement (%)	Standard error (%)	P-valuea)	Mean improvement (%)	Standard error (%)	P-valuea)
Becks depression	54.1	±4.2	<0.0001	30.7	±5.9	<0.001	<0.01
Cohen perceived stress	35.8	±3.3	<0.0001	18.0	±4.3	<0.001	<0.001
Generalized anxiety disorder	51.4	±4.4	<0.0001	27.0	±7.6	<0.001	<0.001
Buss-Perry aggression	17.8	±2.5	0.0001	6.8	±2.8	<0.05	<0.01

^a)P-value for evaluating changes from baseline within treatment group; ^b)P-value for evaluating changes from baseline between oxaloacetate and placebo group (primary analysis).