| Methods |
Random number table, no further information. CFU ‐ A, blinding ‐ C. |
| Participants |
33 primigravid women; no hypertension, renal disease, or other medical problems; no antihypertensive therapy; DBP 110 mmHg or more for 2 hrs; and at least 28 weeks' gestation. Not needing immediate delivery and no fetal distress. |
| Interventions |
Nifedipine: 10 mg oral. Repeated after 30 mins if no response.
Hydralazine: 6.25 mg in 10 mL water IV over 5‐10 mins. Repeated after 30 mins if no response. |
| Outcomes |
Woman: need for second dose, low BP causing fetal distress, side‐effects (headache, flushing nausea, retrosternal pain).
Baby: death. |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
“...they were allocated to one of two groups using a random number table.” |
| Allocation concealment (selection bias) |
Unclear risk |
B ‐ Unclear. Not reported. |
| Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
Not reported, but regimens different. |
| Blinding of outcome assessment (detection bias)
All outcomes |
High risk |
Not reported, but regimens different. |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
Unclear. |
| Selective reporting (reporting bias) |
Low risk |
All expected outcomes reported. |
| Other bias |
Unclear risk |
Unclear. |
