Comparison 3. SSRIs versus placebo: withdrawal due to adverse effects.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Low dose	7	1301	Odds Ratio (M‐H, Random, 95% CI)	1.76 [1.13, 2.75]
1.1 Luteal administration	4	600	Odds Ratio (M‐H, Random, 95% CI)	2.21 [1.05, 4.65]
1.2 Continuous administration	3	701	Odds Ratio (M‐H, Random, 95% CI)	1.56 [0.90, 2.71]
2 Mod dose	15	2447	Odds Ratio (M‐H, Fixed, 95% CI)	2.55 [1.84, 3.53]
2.1 Luteal administration	8	1171	Odds Ratio (M‐H, Fixed, 95% CI)	3.23 [1.82, 5.73]
2.2 Continuous administration	9	1276	Odds Ratio (M‐H, Fixed, 95% CI)	2.24 [1.50, 3.34]
3 High dose	1		Odds Ratio (M‐H, Fixed, 95% CI)	Subtotals only
3.1 Continuous administration	1	231	Odds Ratio (M‐H, Fixed, 95% CI)	6.35 [2.88, 14.00]