Comparison 6. SSRIs versus placebo ‐ psychological symptoms (change scores).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Low dose SSRI	4	683	Std. Mean Difference (IV, Random, 95% CI)	‐0.26 [‐0.42, ‐0.11]
1.1 Luteal administration	3	445	Std. Mean Difference (IV, Random, 95% CI)	‐0.29 [‐0.52, ‐0.07]
1.2 Continuous administration	1	238	Std. Mean Difference (IV, Random, 95% CI)	‐0.20 [‐0.45, 0.06]
2 Moderate dose SSRI	4	681	Std. Mean Difference (IV, Random, 95% CI)	‐0.30 [‐0.48, ‐0.11]
2.1 Luteal administration	3	449	Std. Mean Difference (IV, Random, 95% CI)	‐0.29 [‐0.58, ‐0.01]
2.2 Continuous administration	1	232	Std. Mean Difference (IV, Random, 95% CI)	‐0.31 [‐0.57, ‐0.05]