Comparison 11. SSRIs versus placebo ‐ irritability (end scores).
Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
---|---|---|---|---|
1 Low dose SSRI | 1 | 53 | Std. Mean Difference (IV, Random, 95% CI) | ‐0.57 [‐1.12, ‐0.02] |
1.1 Luteal administration | 1 | 53 | Std. Mean Difference (IV, Random, 95% CI) | ‐0.57 [‐1.12, ‐0.02] |
2 Moderate dose SSRI | 5 | 655 | Std. Mean Difference (IV, Random, 95% CI) | ‐0.56 [‐0.72, ‐0.40] |
2.1 Luteal administration | 2 | 282 | Std. Mean Difference (IV, Random, 95% CI) | ‐0.65 [‐0.93, ‐0.36] |
2.2 Continuous administration | 3 | 373 | Std. Mean Difference (IV, Random, 95% CI) | ‐0.51 [‐0.73, ‐0.30] |