Comparison 12. SSRIs versus placebo ‐ irritability (change scores).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Low dose SSRI	1	169	Std. Mean Difference (IV, Random, 95% CI)	‐0.39 [‐0.70, ‐0.09]
1.1 Luteal administration	1	169	Std. Mean Difference (IV, Random, 95% CI)	‐0.39 [‐0.70, ‐0.09]
2 Moderate dose SSRI	1	169	Std. Mean Difference (IV, Random, 95% CI)	‐0.50 [‐0.80, ‐0.19]
2.1 Luteal administration	1	169	Std. Mean Difference (IV, Random, 95% CI)	‐0.50 [‐0.80, ‐0.19]