Study	Reason for exclusion
Alpay 2001	Not placebo controlled
Brandenburg 1993	Open trial. Not placebo controlled
De la Gandara 1997	Open trial. Not placebo controlled
Diegoli 1998	Quasi‐randomised (by date of presentation)
Elks 1993	Open trial. Not placebo controlled
Flores Ramos 2003	Randomised trial of intermittent and continuous citalopram. Not placebo controlled
Freeman 1996	Open trial. Not placebo controlled
Freeman 1999b	Open trial. Not placebo controlled
Freeman 2000	No extractable symptom data presented; only data on baseline postmenstrual symptoms
Freeman 2002	Open trial. Not placebo controlled
Freeman 2005	Randomised trial but not placebo controlled
Glaxo 2002	Extension study, including only women who completed one of three RCTs and who not experience clinically significant adverse effects
Landen 2009	Unrandomised follow‐up of responders to Landen 2007
Miller 2008	Participants had premenstrual exacerbation of depression and did not have with a prospective diagnosis of PMS or PMDD
Pearlstein 1994	Open trial. Not placebo controlled
Pearlstein 2000	No extractable symptom data presented; only data on psychosocial functioning
Rickels 1990	Not blind, not randomised, placebo group from parallel trial
Steiner 1997	Open trial. Not placebo controlled
Sundblad 1992	Intervention (clomipramine) not an SSRI
Sundblad 1993	Intervention (clomipramine) not an SSRI
Sundblad 1997	Open trial. Not placebo controlled
Veeninga 1990	RCT. Participants were not screened at study entry as to whether they met diagnostic criteria for PMS or PMDD
Wu 2008	No placebo group
Yonkers 1996	Open trial. Not placebo controlled
Yonkers 2002	Not randomised
Yonkers 2006	Randomised crossover trial using paroxetine. However treatment was only administered for one cycle before crossover and one cycle after crossover. Study did not therefore meet review entry criteria