Comparison 12. Treatments for onychomycosis (nail infections).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Treatments versus placebo, treatment failure	4		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1 Ciclopiroxolamine versus placebo. Outcomes at 48 weeks	2	460	Risk Ratio (M‐H, Random, 95% CI)	0.32 [0.20, 0.52]
1.2 Fungoid Tincture versus Placebo. Outcomes at 12 months	1	20	Risk Ratio (M‐H, Random, 95% CI)	0.17 [0.02, 1.14]
1.3 Butenafine 2% & tea tree oil vs placebo. Outcomes at 36 weeks	1	60	Risk Ratio (M‐H, Random, 95% CI)	0.03 [0.00, 0.47]
2 Comparisons between active treatments, treatment failure	1		Risk Ratio (M‐H, Random, 95% CI)	Totals not selected
2.1 Amorolfine 5% + methylene versus Amorolfine 5% + ethanol outcomes at 3 days	1		Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]