Akers 1989.

Methods	RCT Study aim clearly defined: yes Blinded assessor of primary outcome: not stated Double blind study: yes Participants comparable at baseline for age:yes Sex: yes Duration of complaint: yes Inclusion and exclusion criteria specified: yes Interventions well described: yes Assessment of compliance: no Intention to treat analysis: no A Priori sample size calculation: no Fungi identified: yes Distribution of species between groups: not stated Adverse events reported: yes Number of drop outs stated: 30
Participants	Total evaluable sample size: 229
Interventions	a. Sulconazole nitrate 1% cream Duration: four weeks Frequency: applied twice daily b. Placebo cream Duration: four weeks Frequency: applied twice daily
Outcomes	Primary outcome: Cure Secondary Outcomes: Signs and symptoms ‐ itching, erythems, scaling, fissuring, exudation, pustules, maceration, vesiculation
Notes	Chronic moccasin type tinea pedis. Data extracted for T. rubrum only (92% of those with + ve cultures)
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk	A ‐ Adequate