Akers 1989.
Methods | RCT Study aim clearly defined: yes Blinded assessor of primary outcome: not stated Double blind study: yes Participants comparable at baseline for age:yes Sex: yes Duration of complaint: yes Inclusion and exclusion criteria specified: yes Interventions well described: yes Assessment of compliance: no Intention to treat analysis: no A Priori sample size calculation: no Fungi identified: yes Distribution of species between groups: not stated Adverse events reported: yes Number of drop outs stated: 30 | |
Participants | Total evaluable sample size: 229 | |
Interventions | a. Sulconazole nitrate 1% cream Duration: four weeks Frequency: applied twice daily b. Placebo cream Duration: four weeks Frequency: applied twice daily | |
Outcomes | Primary outcome: Cure Secondary Outcomes: Signs and symptoms ‐ itching, erythems, scaling, fissuring, exudation, pustules, maceration, vesiculation | |
Notes | Chronic moccasin type tinea pedis. Data extracted for T. rubrum only (92% of those with + ve cultures) |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Low risk | A ‐ Adequate |