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. 2007 Jul 18;2007(3):CD001434. doi: 10.1002/14651858.CD001434.pub2

Chretien 1980.

Methods RCT
 Study aim clearly defined: yes
 Blinded assessor of primary outcome: not stated 
 Double blind study: yes
 Participants comparable at baseline for age: yes Sex: not stated Duration of complaint: yes
 Inclusion and exclusion criteria specified: yes
 Interventions well described: yes
 Assessment of compliance: not stated
 Reoccurrence status: yes
 Intention to treat analysis: not stated
 A Priori sample size calculation: not stated
 Fungi identified: yes
 Distribution of species between groups: yes
 Adverse events reported: not stated
 Number of drop outs stated: not stated
Participants Total evaluable sample size: 85
Interventions A. 2% undecylenic acid and 20% zinc acid powder
Duration: four weeks
 Frequency: applied twice daily
b. Placebo powder 
 Duration: four weeks
 Frequency: applied twice daily
Outcomes Primary outcome: cure
 Secondary outcomes:signs and symptoms ‐ erthythema, scaling, fissuring, hyperkeratosis
Notes Culture results only
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk D ‐ Not used