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. 2007 Jul 18;2007(3):CD001434. doi: 10.1002/14651858.CD001434.pub2

Holti 1970.

Methods RCT
 Study aim clearly defined: yes
 Blinded assessor of primary outcome: yes 
 Double blind study: yes
 Participants comparable at baseline for age: not stated Sex: not stated Duration of complaint: not stated
 Inclusion and exclusion criteria specified: yes
 Interventions well described: yes
 Assessment of compliance: not stated
 Intention to treat analysis: not stated
 A Priori sample size calculation: not stated
 Fungi identified: yes
 Distribution of species between groups: yes
 Adverse events reported: yes
 Number of drop outs stated: not stated
Participants Total evaluable sample size: 12
 Treatment setting: multicentre
Interventions a. Whitfields ointment
 Duration: eight weeks
 Frequency: once daily
 b. Varotin ointment
 Duration: eight weeks
 Frequency: once daily
Outcomes Primary outcome: cure
 Adverse events: none
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear