| Methods |
RCT
Study aim clearly defined: yes
Blinded assessor of primary outcome: not stated
Single blind study
Participants comparable at baseline for age: yes Sex: yes Duration of complaint: not stated
Inclusion and exclusion criteria specified: yes
Interventions well described: yes
Assessment of compliance: not stated
Intention to treat analysis: not stated
A Priori sample size calculation: not stated
Fungi identified: yes
Distribution of species between groups: no
Adverse events reported: yes
Number of drop outs stated: 55 |
| Participants |
Total evaluable sample size: 379
Exclusion criteria: Hyperkeratotic tinea pedis
use of systemic antifungals one month prior to study
use of topical antifungals one week prior to study |
| Interventions |
a. Naftifine
Duration: five weeks
Frequency: applied twice daily
b. Clotrimazole
Duration: five weeks
Frequency: applied twice daily |
| Outcomes |
Primary outcome: cure
Secondary Outcomes: Signs and symptoms
‐ itching, erythema, scaling, exudation, papules, vesiculation, erosion
Global efficacy
Adverse events: slight |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Unclear risk |
B ‐ Unclear |
