Smith 1977.
Methods | RCT Study aim clearly defined: yes Blinded assesor of primary outcome: yes Double blind study: yes Participants comparable at baseline for age: yes Sex: not stated Duration of complaint: yes Inclusion and exclusion criteria specified: not stated Interventions well described: yes Assessment of compliance: yes Intention to treat analysis: yes A Priori sample size calculation: not stated Fungi identified: yes Distribution of species between groups: not stated Adverse events reported: yes Number of drop outs stated: nine | |
Participants | Total evaluable sample size: 104 Treatment setting: Health Center | |
Interventions | a. 20% zinc undecylenate and 2% undecylenic acid ‐ new commercial powder Duration: six weeks Frequency: applied once daily b. 20% Undecylenate and 2% undecylenic acid ‐ over the counter powder Duration: six weeks Frequency: applied once daily c. Placebo powder Duration: six weeks Frequency: applied once daily | |
Outcomes | Primary outcome: cure Adverse events: a. two patients with pruritus | |
Notes | Culture results only | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Low risk | A ‐ Adequate |