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. 2007 Jul 18;2007(3):CD001434. doi: 10.1002/14651858.CD001434.pub2

Vermeer 1996.

Methods RCT
 Study aim clearly defined: yes
 Blinded assessor of primary outcome: not stated 
 Double blind study:yes
 Participants comparable at baseline for age: yes Sex: yes Duration of complaint: yes
 Inclusion and exclusion criteria specified: yes
 Interventions well described: yes
 Assessment of compliance: not stated
 Intention to treat analysis: not stated
 A Priori sample size calculation: not stated
 Fungi identified: yes
 Distribution of species between groups: no
 Adverse events reported: no
 Number of drop outs stated: no
Participants Total evaluable sample size: 191
 Treatment setting: Department of Dermatology (hospital)
Interventions a. Terbinafine cream
 Duration: one week plus one week Placebo
 Frequency:
 b. Miconazole cream
 Duration: four weeks
 Frequency:
Outcomes Primary outcome: cure
 Secondary Outcomes: Signs and symptoms
 ‐ itching, erythema, scaling, vesiculation
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear