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. 2020 Mar 11;13:2203–2213. doi: 10.2147/OTT.S247015

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© 2020 Wan et al.

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Smad4 variants affect the migration of A549 cells. (A) Representative images show the wound-healing detected on time point 0 h and 72 h in A549 cells that recombinantly express wildtype Smad4 or its variants as indicated. (B) Bar graphs show the normalized migrated distance of A549 cells as indicated in panel A. n=4, Error bars: Mean±SD. *P<0.05, **P<0.01, ***P<0.001.